© Copyright 2026 American Medical Association. All rights reserved.
High dose rate (HDR) electronic brachytherapy is a specialized form of radiation therapy that utilizes an x-ray tube to deliver electronically generated photons as the radiation source. This innovative approach eliminates the need for traditional radioactive isotopes, making the procedure safer and more efficient. HDR electronic brachytherapy is primarily indicated for the treatment of breast cancer, particularly following a lumpectomy, where the goal is to target and destroy any remaining cancerous cells in the tumor bed. The procedure involves the insertion of a brachytherapy applicator device into the body, either directly into the tissue surrounding the tumor (intrastitial) or into a body cavity (intracavitary). This precise placement allows for targeted radiation delivery to the affected area. Before treatment, the radiation oncologist assesses the target volume that requires treatment and determines the appropriate dose of radiation. This planning phase may involve the use of computerized brachytherapy dosimetry to refine the treatment plan, ensuring optimal delivery of radiation while minimizing exposure to surrounding healthy tissues. During the procedure, a shielding device is applied to protect normal tissue from radiation exposure, and additional external shielding may be utilized as necessary. The control panel is set to deliver the prescribed dose, and the x-ray generator is activated to administer the high dose electronic brachytherapy to the tumor or tumor bed for a specified duration, typically ranging from 10 to 40 minutes. The treatment is divided into fractions, with a standard regimen following lumpectomy consisting of 10 fractions delivered over five days, with two fractions administered each day. Each fraction is reported separately, and the brachytherapy applicator remains in place until the completion of the entire treatment course.
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