© Copyright 2026 American Medical Association. All rights reserved.
Near-infrared spectroscopy (NIRS) is a non-invasive diagnostic technique that employs near-infrared light to assess the healing process of wounds located in the lower extremities. This method is particularly beneficial for monitoring diabetic ulcers, which are known for their challenging healing trajectories. During the NIRS procedure, a specialized device is utilized to measure the concentration of oxyhemoglobin beneath the surface of the skin at the wound site, as well as at a control site on healthy tissue, typically assessed on a weekly basis. The data obtained from these measurements provide critical insights into the wound's healing potential. Wounds that are likely to heal exhibit a consistent decrease in hemoglobin concentration over time, often beginning several weeks before the actual closure of the wound. As the healing process advances, the hemoglobin levels at the wound site tend to converge towards those observed at the healthy control site. Conversely, wounds that are not healing effectively will show persistently elevated hemoglobin levels when compared to the control site, indicating a lack of progress in the healing process. This technique serves as a valuable tool for healthcare professionals in evaluating and managing wound care effectively.
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