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Official Description

Optical coherence tomography of breast or axillary lymph node, excised tissue, each specimen; real-time intraoperative

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Optical coherence tomography (OCT) is a sophisticated, non-invasive imaging technique that provides high-resolution images of the microscopic structures within breast tissue and axillary lymph nodes during surgical procedures. This advanced imaging modality employs near-infrared light to capture detailed images in real-time, allowing for the differentiation between lymphatic tissue and adipose (fat) tissue. By visualizing the intricate architecture of lymph nodes, including features such as germinal centers and intranodal lymph and blood vessels, OCT plays a crucial role in identifying the presence of metastatic disease. The intraoperative application of OCT is particularly beneficial in breast cancer surgeries, as it can significantly reduce the number of non-diseased lymph nodes that are excised. This reduction not only minimizes the risk of complications, such as lymphedema, but also aids in monitoring tumor margins, which is essential for conserving healthy breast tissue during surgical removal. Consequently, this technique can lead to less extensive breast reconstruction procedures. The CPT® Code 0351T specifically designates the real-time intraoperative use of optical coherence tomography for excised breast or axillary lymph node tissue specimens.

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