© Copyright 2026 American Medical Association. All rights reserved.
Optical coherence tomography (OCT) is a sophisticated, non-invasive imaging technique that is employed during surgical procedures to provide real-time visualization of the microscopic features of breast tissue and the surrounding surgical cavity. This advanced imaging modality utilizes high-resolution, near-infrared light to capture detailed images of tissue microstructure. By distinguishing between normal low-scattering adipocytes, which are typical in healthy breast tissue, and high-scattering, heterogeneous patterned tissue that is indicative of tumor cells, OCT plays a crucial role in surgical oncology. The intraoperative application of OCT allows surgeons to make informed decisions regarding the conservation of breast tissue during tumor removal, thereby optimizing the chances of achieving clear surgical margins. The specific CPT® code 0353T is designated for this real-time intraoperative procedure, while the subsequent physician interpretation and reporting of the findings are captured under code 0354T.
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