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Code deleted, see 33277, 33287, 33288.

Official Description

Insertion or replacement of neurostimulator system for treatment of central sleep apnea; sensing lead only

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 0425T involves the insertion or replacement of a neurostimulator system specifically designed for the treatment of central sleep apnea (CSA). Central sleep apnea is a condition characterized by the temporary cessation of breathing due to the brain's failure to signal the muscles responsible for respiration. This condition can be exacerbated by various factors, including cardiovascular diseases, strokes, anatomical issues affecting the neck or brainstem, morbid obesity, and the use of narcotic medications. The neurostimulator system comprises an implantable pulse generator (IPG), which is typically placed in a subcutaneous pocket in the pectoral region, often on the right side of the body. Additionally, the system includes a stimulation lead that is positioned in either the right brachiocephalic vein or the left pericardiophrenic vein (the latter being the preferred site) to facilitate unilateral phrenic nerve stimulation. A pressure sensing lead is also inserted into the azygos vein to monitor respiratory activity. The primary function of the IPG is to deliver electrical impulses to the phrenic nerve, thereby inducing contractions of the diaphragm and restoring normal breathing patterns. This procedure is performed under conscious sedation, allowing for patient-physician communication throughout the process.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure is indicated for patients diagnosed with central sleep apnea (CSA), which may arise from various underlying conditions. The following factors may contribute to the occurrence of CSA:

  • Cardiovascular Disease: Conditions affecting the heart and blood vessels can disrupt normal respiratory function.
  • Stroke: Neurological impairments resulting from a stroke can interfere with the brain's ability to regulate breathing.
  • Conditions Affecting the Neck or Brainstem: Anatomical or pathological issues in these areas can impact the signals sent to the respiratory muscles.
  • Morbid Obesity: Excess body weight can lead to respiratory complications, including CSA.
  • Narcotic Use: The use of narcotic medications can depress the central nervous system, affecting breathing patterns.

2. Procedure

The procedure for the insertion or replacement of the neurostimulator system involves several detailed steps to ensure proper placement and functionality:

  • Step 1: The procedure begins with the patient receiving conscious sedation, allowing them to remain communicative during the process. Access to the right side venous system is achieved through a small incision made in the right axillary, cephalic, or subclavian vein.
  • Step 2: A sheath is placed in the vein, and two long access wires are advanced into the vena cava. This step is crucial for establishing a pathway for subsequent catheter placement.
  • Step 3: A guide catheter is then delivered over one of the access wires into the superior vena cava and advanced into the left brachiocephalic vein (LBC), positioning the tip at the junction with the left subclavian vein.
  • Step 4: Using contrast material, venous branches are identified, and an inner catheter is threaded into the guide catheter, extending beyond it to facilitate access to the pericardiophrenic vein (PPV).
  • Step 5: The opening of the PPV is visualized and accessed with a coronary wire while the patient is instructed to take deep breaths, which aids in the advancement of the wire.
  • Step 6: The guide catheter is further advanced, and the inner catheter is removed. The stimulation lead is then loaded into the guide catheter and deployed to the targeted location within the PPV.
  • Step 7: The sensing lead is deployed next. This involves threading a coronary sinus right guide catheter over the second venous access wire to a position between the tracheal carina and the junction of the brachiocephalic veins.
  • Step 8: The opening of the azygos vein is visualized using contrast, and a wire is advanced to the diaphragm level, again utilizing deep breaths or coughing to facilitate this step.
  • Step 9: An inner catheter is advanced over the wire, followed by the guide catheter, which is then advanced to the right lateral branch of the azygos vein for the deployment of the sensing lead.
  • Step 10: After lead placement, the effectiveness of the stimulation is assessed to ensure complete contraction of the hemidiaphragm.
  • Step 11: The pulse generator is connected to the implanted leads and is placed in a subcutaneous pocket created below the clavicle. The unit is secured in place with a single ligature.
  • Step 12: Finally, the functionality of the neurostimulator unit is checked to confirm that it operates correctly.

3. Post-Procedure

Post-procedure care involves monitoring the patient for any immediate complications and ensuring that the neurostimulator system is functioning as intended. Patients may be advised on activity restrictions and follow-up appointments to assess the effectiveness of the treatment. It is essential to provide education on the signs of potential complications, such as infection or lead displacement, and to ensure that the patient understands the importance of adhering to follow-up care for optimal outcomes.

Short Descr INSJ/RPLC NSTIM APNEA SEN LD
Medium Descr INSJ/RPLC NSTIM SYSTEM SLEEP APNEA SENSING LEAD
Long Descr Insertion or replacement of neurostimulator system for treatment of central sleep apnea; sensing lead only
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE Not applicable/unspecified.
Date
Action
Notes
2023-12-31 Deleted Code deleted, see 33277, 33287, 33288.
2017-01-01 Added First appearance in codebook.
2016-01-01 Added Added
Code
Description
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