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Official Description

Injection(s), autologous white blood cell concentrate (autologous protein solution), any site, including image guidance, harvesting and preparation, when performed

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 0481T involves the injection of autologous white blood cell concentrate, also referred to as autologous protein solution, into various anatomical sites, including joints, tissues, or bones. This technique is designed to leverage the body's own healing capabilities by utilizing concentrated white blood cells, which are known to play a crucial role in the inflammatory response and tissue repair processes. The autologous protein solution is derived from the patient's own blood, ensuring compatibility and reducing the risk of adverse reactions. The procedure typically includes several key components: the harvesting of blood from a peripheral vein, the preparation of the white blood cell concentrate through centrifugation or filtration, and the actual injection of the prepared solution into the targeted area. This method is particularly beneficial for treating a range of conditions, including inflammatory and overuse injuries such as tendonitis, bursitis, and fasciitis, as well as degenerative diseases like osteoarthritis. By enhancing the natural healing mechanisms of the body, this procedure aims to facilitate a more rapid and efficient restoration of healthy tissue, ultimately improving patient outcomes.

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