© Copyright 2026 American Medical Association. All rights reserved.
Transcatheter mitral valve implantation/replacement (TMVI) with a prosthetic valve is a minimally invasive surgical procedure designed to address mitral valve disorders, specifically targeting conditions such as primary (degenerative) and secondary (functional) mitral regurgitation, as well as mitral valve stenosis. This procedure allows for the replacement or implantation of a mitral valve without the need for traditional open-heart surgery, thereby reducing recovery time and associated risks. TMVI can be performed through various approaches, including a percutaneous retrograde transapical approach, a percutaneous antegrade transfemoral approach, or via transthoracic thoracotomy using a transapical technique. Each method involves accessing the heart through different anatomical pathways, with the goal of delivering a prosthetic valve to restore normal function to the mitral valve. The procedure is guided by imaging techniques such as transesophageal echocardiography and angiography to ensure accurate placement of the valve. The use of rapid ventricular pacing during deployment of the valve aids in its proper positioning, enhancing the overall success of the procedure.
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