© Copyright 2026 American Medical Association. All rights reserved.
Magnetic resonance spectroscopy (MRS) is a non-invasive imaging technique that provides detailed biochemical information about intervertebral discs in the cervical, thoracic, or lumbar regions of the spine. This procedure is specifically designed to determine and localize discogenic pain, which is pain originating from the intervertebral discs. The MRS technique utilizes advanced post-processing software to analyze biomarker data obtained from the discs. This analysis involves several critical steps aimed at enhancing the quality and accuracy of the spectral data. These steps include optimal channel selection, phase error correction, frame editing, frequency shift correction, apodization, coherent averaging, baseline correction, and artifact filtering. The proprietary software evaluates the MRS data to ensure optimal signal quality and to meet voxel criteria, which helps to avoid issues such as bone overlap and insufficient signal-to-noise ratio (SNR). The end result of this meticulous processing is the quantification of various metabolites or biomarkers within the discs, expressed as peak values or ratios. These values reflect the relative chemical differences between the discs, providing valuable insights into their condition and potential pain sources. The interpretation and reporting of this MRS disc biomarker data are captured under CPT® Code 0612T, which signifies the comprehensive analysis performed to aid in diagnosing discogenic pain.
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