© Copyright 2026 American Medical Association. All rights reserved.
Noncontact near-infrared spectroscopy (NIRS) is a sophisticated imaging technique utilized for the assessment of wounds and skin flap oxygen perfusion through the application of light. This method enables the calculation of the percentages of oxygenated hemoglobin (oxyhemoglobin) and deoxygenated hemoglobin (deoxyhemoglobin), as well as the ratio of tissue oxygenation (StO2). These measurements are critical for predicting wound healing, evaluating the viability of skin flaps, and determining the success of biologic wound matrix applications. The principle behind NIRS is based on the relative transparency of tissue to near-infrared light, which reflects differently depending on the oxygenation levels present in the blood. By utilizing a noncontact hand-held imaging device, such as SnapshotNIR, healthcare professionals can measure the oxygenation levels within the capillary bed without direct contact with the skin. The device emits six near-infrared electromagnetic wavelengths of light, which are absorbed variably by oxygenated and deoxygenated hemoglobin molecules. The light that is not absorbed is reflected back to the device, where it is recorded for analysis. Proprietary calculation software processes the return signal to assess the oxygen saturation level at each pixel, resulting in a color-coded map that visually represents the oxygenation status alongside the clinical image. This data is then interpreted to generate a comprehensive report detailing the healing progress or viability of the flap, as well as predicting the healing trajectory. Such information is invaluable in mitigating risks associated with wound healing and enhancing patient outcomes.
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