© Copyright 2026 American Medical Association. All rights reserved.
Quantitative magnetic resonance (QMR) is a sophisticated imaging technique designed for the analysis of tissue composition, including fat, iron, water content, and other components within a specific organ or tissue. This method offers enhanced precision compared to traditional imaging studies, such as dual-energy X-ray absorptiometry (DXA), making it particularly valuable in various clinical scenarios. QMR is instrumental in detecting subtle changes in body composition, which can be critical for evaluating the effectiveness of medical treatments, nutritional interventions, and monitoring chronic diseases. Additionally, it aids in assessing growth patterns or changes in the target area over time.
The QMR technique leverages the unique nuclear magnetic resonance properties of hydrogen atoms found in different types of tissues. By utilizing these properties, QMR can differentiate between signals originating from fat, lean tissue, bone, and water. During the procedure, the patient is positioned on a rolling bed that moves into a specialized square bore chamber, which is enveloped by a resistive electromagnet. This magnet creates a static, low-intensity magnetic field that is essential for the imaging process. Radiofrequency pulses are then directed at the target tissue, stimulating the hydrogen nuclei within the magnetic field. As these nuclei relax, they emit electromagnetic signals that reflect their surrounding environment. These signals are captured and processed to extract quantitative data, which is further analyzed through algorithms to produce parametric mapping of the tissue composition.
Following the data acquisition, all metrics are meticulously reviewed and interpreted, often in comparison to previous studies, to ensure accuracy and relevance. A comprehensive report is generated, detailing the findings of the QMR analysis. Additionally, separate MRI sequences of the target organ(s) are performed to evaluate any potential changes or lesions. It is important to report CPT® Code 0649T for single organ QMR analysis of tissue composition in conjunction with a diagnostic MRI of the same anatomy during the same session, while CPT® Code 0698T should be reported for multiple organ QMR analysis with diagnostic MRI of the same anatomy. This procedure is billed in addition to the primary procedure, ensuring that all relevant analyses are captured for proper documentation and reimbursement.
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