CPT® Code 0717T

Autologous adipose-derived regenerative cell (ADRC) therapy for partial thickness rotator cuff tear; adipose tissue harvesting, isolation and preparation of harvested cells, including incubation with cell dissociation enzymes, filtration, washing, and concentration of ADRCs

Autologous adipose-derived regenerative cell (ADRC) therapy is a medical procedure designed to address partial thickness rotator cuff tears by utilizing the patient's own adipose (fat) tissue. This innovative approach aims to enhance the healing process of the tendons surrounding the shoulder joint. Traditional conservative treatments, such as physical therapy or steroid injections, may alleviate symptoms but do not facilitate the actual repair of a torn rotator cuff. Surgical interventions can be effective; however, they carry a significant risk of re-rupture. One contributing factor to the rotator cuff's limited healing capacity is the inadequate supply of stem cells, which are essential for the development of connective tissue, lymphatic tissue, or blood vessels at the tendon-bone interface. The ADRC therapy process involves several critical steps, including the harvesting, cleaning, filtering, and processing of adipose tissue. Initially, adipose tissue is obtained from the patient, typically through a procedure known as liposuction, which is performed under local anesthesia in areas such as the trunk or thigh. Once harvested, the adipose tissue is allowed to rest, enabling it to separate into distinct components. The tissue then undergoes incubation with specific enzymatic reagents that facilitate cell isolation and dissociation. Following this, the cells are meticulously processed through a series of steps that include filtration, washing, and centrifugation to concentrate the autologous adipose-derived regenerative cells. Ultimately, these prepared cells are injected into the supraspinatus tendon, which is a critical component of the rotator cuff, using an appropriate gauge needle under ultrasonic guidance. The injection site is subsequently dressed to promote healing. While the full efficacy of this procedure is still being explored in clinical trials, preliminary findings indicate promising outcomes in the repair of partially torn rotator cuffs, with a low incidence of side effects and re-tears.