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A xenograft implantation into the articular surface involves the use of a scaffold or implant derived from a non-human animal, specifically designed to repair lesions in the cartilage of a joint surface that have been affected by osteoarthritis. This procedure serves as an alternative to traditional methods such as autografts, which are harvested from the patient’s own body, or allografts, which are sourced from a bone bank. The xenograft, often made from porcine joint cartilage, is meticulously prepared prior to implantation. This preparation includes thorough cleansing and decellularization of cylindrical xenograft osteochondral plugs to eliminate all antigens, thereby minimizing the risk of rejection by the patient's immune system. The surgical process begins with a skin incision over the affected joint compartment, such as the knee, allowing access to the joint capsule. Once the joint is accessed, the surgeon inspects the surfaces to identify the specific area of cartilage damage. The extent of the damage is measured, and the number of grafts needed for effective repair is determined. Following this assessment, the damaged cartilage is debrided, drilled, and prepared to receive the osteochondral xenografts. The surgeon then customizes one or more xenografts to fit the defect in the articular surface, ensuring they are properly placed and stabilized. After confirming the stability of the grafts through range of motion checks, the surgical tools and arthroscope are removed, and the portal incisions are closed, completing the procedure.
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