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Official Description

Punch biopsy of skin (including simple closure, when performed); each separate/additional lesion (List separately in addition to code for primary procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A punch biopsy is a medical procedure used to obtain a cylindrical sample of skin tissue for diagnostic purposes. This technique is particularly useful for evaluating various skin lesions, which may include pigmented nevi (moles), superficial inflammatory dermatoses (skin conditions characterized by inflammation), papulosquamous disorders (conditions that cause raised, scaly patches), granulomatous diseases (inflammatory conditions that result in the formation of granulomas), bullous disorders (conditions that cause blisters), connective tissue disorders, and benign tumors that appear non-cancerous. During the procedure, the skin is first anesthetized to minimize discomfort. A punch tool, which is a circular instrument of varying sizes, is selected based on the lesion's dimensions. The skin is then stretched perpendicular to the natural tension lines to facilitate a clean cut. The punch tool is applied to the skin and rotated to penetrate through the epidermis and into the reticular dermis and subcutaneous fat, capturing a full-thickness sample. Once the punch tool is removed, the edge of the specimen is grasped with forceps, lifted, and excised at the base using scissors. To manage any bleeding that may occur, methods such as electrocautery, aluminum chloride, or Monsel’s solution can be employed. After the biopsy, the resulting defect may be closed using simple sutures, staples, gelfoam, or adhesive bandages, which may include basic techniques to approximate the edges of the wound for optimal healing. It is important to note that CPT® Code 11104 is used to report a single lesion removed by punch biopsy, including any simple closure performed, while CPT® Code 11105 is designated for each additional lesion biopsied during the same session.

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