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Official Description

Excision, malignant lesion including margins, scalp, neck, hands, feet, genitalia; excised diameter 0.6 to 1.0 cm

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 11621 refers to the excision of a malignant lesion located on specific areas of the body, including the scalp, neck, hands, feet, or genitalia. This procedure involves the removal of the malignant tissue along with a margin of healthy tissue to ensure complete excision of the cancerous cells. Common types of malignant lesions that may be excised using this code include basal cell carcinoma, squamous cell carcinoma, verrucous carcinoma, and melanoma. The procedure begins with the cleansing of the affected area, followed by the administration of a local anesthetic to minimize discomfort during the excision. A full-thickness incision is then made through the dermis, carefully encircling the lesion to remove it entirely. To confirm that the excised margins are free of malignant cells, a frozen section may be performed during the procedure. If any malignant tissue is detected at the margins, additional tissue will be excised until clear margins are achieved. The excised lesion is subsequently sent to a laboratory for histologic evaluation, which is also reportable separately. To manage any bleeding that may occur during the procedure, electrocautery or chemical cautery techniques are employed. Finally, the surgical wound may be closed using a simple single-layer suture technique, although more complex closure methods such as intermediate (layer) closure, complex repair, skin grafts, or pedicle flaps may also be utilized depending on the specific circumstances of the excision.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 11621 is indicated for the excision of malignant lesions located on the scalp, neck, hands, feet, or genitalia. These lesions may present as:

  • Basal Cell Carcinoma - A common form of skin cancer that typically appears as a small, shiny bump or a sore that does not heal.
  • Squamous Cell Carcinoma - A type of skin cancer that may appear as a firm, red nodule or a flat lesion with a scaly, crusted surface.
  • Verrucous Carcinoma - A variant of squamous cell carcinoma that is characterized by a warty appearance and is often found in the oral cavity or on the skin.
  • Melanoma - A serious form of skin cancer that develops from melanocytes and can appear as a new or changing mole.

2. Procedure

The procedure for excising a malignant lesion as described by CPT® Code 11621 involves several critical steps:

  • Step 1: Preparation - The area surrounding the malignant lesion is thoroughly cleansed to reduce the risk of infection. A local anesthetic is then injected to ensure the patient remains comfortable throughout the procedure.
  • Step 2: Incision - A full-thickness incision is made through the dermis, carefully encircling the lesion. This incision is designed to include a margin of healthy tissue surrounding the malignant area to ensure complete removal.
  • Step 3: Excision - The entire lesion, along with the surrounding healthy tissue, is excised. This step is crucial for ensuring that all cancerous cells are removed from the body.
  • Step 4: Frozen Section Analysis - If necessary, a frozen section may be performed during the excision to evaluate the margins for any remaining malignant cells. If malignant tissue is found at the margins, additional tissue will be excised until clear margins are confirmed.
  • Step 5: Laboratory Evaluation - The excised lesion is sent to a laboratory for histologic evaluation, which is reportable separately. This evaluation helps in determining the nature of the lesion and ensuring that it has been completely removed.
  • Step 6: Hemostasis - Any bleeding that occurs during the procedure is controlled using electrocautery or chemical cautery techniques to minimize blood loss.
  • Step 7: Wound Closure - The surgical wound may be closed using a simple single-layer suture technique. Depending on the complexity of the excision, other closure methods such as intermediate (layer) closure, complex repair, skin grafts, or pedicle flaps may also be employed.

3. Post-Procedure

After the excision procedure, patients are typically monitored for any immediate complications, such as excessive bleeding or infection. Instructions for post-procedure care will be provided, which may include keeping the surgical site clean and dry, monitoring for signs of infection, and managing pain with prescribed medications. Follow-up appointments may be scheduled to assess the healing process and to discuss the results of the histologic evaluation. It is important for patients to adhere to the post-operative care instructions to promote optimal healing and recovery.

Short Descr EXC S/N/H/F/G MAL+MRG 0.6-1
Medium Descr EXCISION MALIGNANT LESION S/N/H/F/G 0.6-1.0 CM
Long Descr Excision, malignant lesion including margins, scalp, neck, hands, feet, genitalia; excised diameter 0.6 to 1.0 cm
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5A - Ambulatory procedures - skin
MUE 2
CCS Clinical Classification 170 - Excision of skin lesion
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
F1 Left hand, second digit
F2 Left hand, third digit
F3 Left hand, fourth digit
F5 Right hand, thumb
F6 Right hand, second digit
F7 Right hand, third digit
F8 Right hand, fourth digit
FA Left hand, thumb
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
LT Left side (used to identify procedures performed on the left side of the body)
PN Non-excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q8 Two class b findings
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
T7 Right foot, third digit
TA Left foot, great toe
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2003-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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