Coding Ahead
CasePilot
Medical Coding Assistant
CaseConsultant
Instant Email Coding Consultant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account
0 code page views remaining. Guest accounts are limited to 1 page view. Register free account to get 5 more views.
Log in Register free account

Official Description

Full thickness graft, free, including direct closure of donor site, scalp, arms, and/or legs; each additional 20 sq cm, or part thereof (List separately in addition to code for primary procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 15221 involves the harvesting of a full-thickness skin graft from a designated donor site, which may include areas such as the scalp, arms, and/or legs. A full-thickness graft is characterized by its inclusion of all layers of the skin, which encompasses the epidermis, dermis, and subcutaneous fat, along with associated blood vessels. This type of graft is typically utilized in surgical procedures to repair larger defects or wounds where a more robust skin coverage is required. Following the harvesting of the graft, the donor site is meticulously closed to promote healing and minimize scarring. The harvested graft is then positioned over the defect area, ensuring proper alignment and coverage. The edges of both the defect and the graft are secured in place using sutures, facilitating the integration of the graft into the surrounding tissue. It is important to note that CPT® Code 15221 is specifically used to report each additional 20 square centimeters, or part thereof, of the grafted area beyond the initial coverage provided by CPT® Code 15220, which accounts for the first 20 square centimeters of grafting on the scalp, arms, or legs.

© Copyright 2026 Coding Ahead. All rights reserved.

CasePilot
Have a question about CPT® Code 15221?

Get instant expert-level answers from CasePilot, our coding assistant.

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

Register to view content

Create a free account to unlock this content

CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"