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Official Description

Acellular dermal allograft, trunk, arms, legs; first 100 sq cm or less, or 1% of body area of infants and children

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

An acellular dermal allograft is a specialized type of skin graft utilized to cover skin defects located on the trunk, arms, or legs. This graft is derived from cadaveric skin that has undergone a chemical treatment process to remove the epidermal cellular components, which are responsible for triggering immune responses. By eliminating these antigenic components, the likelihood of the graft being rejected by the recipient's immune system is significantly reduced. Initially developed for the treatment of burn victims, acellular dermal allografts have expanded in application to include reconstructive surgery, dental and oral procedures, as well as various plastic and cosmetic surgeries. The procedure involves the careful preparation of the graft, which is typically packaged in sheets. These sheets are rehydrated using an isotonic sodium chloride solution to restore their pliability before being trimmed to fit the specific dimensions of the wound. Once prepared, the graft is applied to the cleaned and prepared wound bed, either in a single layer or multiple layers, and is secured in place with absorbable sutures. Any excess material around the edges of the wound is trimmed to ensure a proper fit. Additionally, the graft may be covered with a separately reportable skin flap if necessary. After the graft is in place, a layered dressing is applied, which includes a bulky gauze layer, a compression layer, and an anti-shear layer to protect the graft and promote healing. The CPT® Code 15330 is specifically designated for the first 100 square centimeters of grafting in adults or for 1% of total body surface area in infants and children, while 15331 is used for each additional 100 square centimeters or 1% of total body surface area thereafter.

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