© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 17264 refers to the destruction of a malignant lesion located on the trunk, arms, or legs, specifically when the diameter of the lesion measures between 3.1 to 4.0 cm. Malignant lesions, which are abnormal growths that can invade surrounding tissues and potentially spread to other parts of the body, are typically treated through excision. However, certain types of malignant lesions, such as squamous cell carcinoma and verrucous carcinoma, as well as those that have not penetrated deeper layers of the dermis, may be effectively treated using various destruction techniques. The procedure begins with a thorough examination of the lesion to determine the most suitable method of destruction. Local anesthesia may be administered to ensure patient comfort during the procedure. Common techniques for lesion destruction include cryosurgery, which involves the application of liquid nitrogen to freeze the lesion, and surgical curettage, which may be followed by electrosurgery to remove the lesion. Other methods include chemosurgery, where a chemical or pharmacologic agent is used to destroy the lesion, and laser destruction, often utilizing a carbon dioxide laser. It is important to note that there are specific CPT® codes designated for lesions of varying sizes, with 17264 specifically applicable for those measuring between 3.1 to 4.0 cm in diameter.
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