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Official Description

Excision of breast lesion identified by preoperative placement of radiological marker, open; single lesion

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 19125 involves the excision of a breast lesion that has been identified through preoperative placement of a radiological marker. This technique is particularly utilized for nonpalpable lesions, which are abnormalities in the breast that cannot be felt during a physical examination but have been detected via imaging studies such as mammograms or ultrasounds. The placement of a radiological marker serves as a precise guide for the surgeon during the excision process. The physician makes an incision in the breast tissue, using the marker to accurately locate the lesion. Following the incision, the surgeon excises the lesion along with a margin of surrounding healthy breast tissue to ensure complete removal of the abnormality. To manage any bleeding that may occur during the procedure, the surgeon employs techniques such as electrocautery or ligation. In some cases, a drain may be placed to facilitate the removal of any excess fluid that could accumulate postoperatively. Finally, the surgical site is closed using layered sutures to promote optimal healing. It is important to note that CPT® Code 19125 is specifically designated for the excision of the first lesion, while CPT® Code 19126 should be used for each additional lesion that is separately identified by a radiological marker.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The excision of a breast lesion identified by preoperative placement of a radiological marker is indicated for specific conditions where nonpalpable lesions have been detected. These indications include:

  • Nonpalpable Breast Lesions Lesions that cannot be felt during a physical examination but have been identified through imaging techniques such as mammography or ultrasound.
  • Suspicious Findings Areas of concern that appear abnormal on imaging studies and require further evaluation through excision to determine the nature of the lesion.
  • Biopsy Confirmation Situations where a biopsy has indicated the presence of a lesion that necessitates surgical removal for definitive diagnosis and treatment.

2. Procedure

The procedure for excising a breast lesion identified by a radiological marker involves several critical steps, which are detailed as follows:

  • Step 1: Preoperative Preparation Prior to the surgical procedure, the patient undergoes imaging studies, such as a mammogram or ultrasound, to identify the nonpalpable lesion. A radiological marker is then placed at the site of the lesion to guide the surgeon during the excision.
  • Step 2: Incision The surgeon makes an incision in the breast tissue, using the radiological marker as a reference point to accurately locate the lesion. This incision is carefully planned to minimize scarring and ensure access to the area of concern.
  • Step 3: Excision of the Lesion The surgeon excises the lesion along with a margin of normal breast tissue surrounding it. This margin is critical to ensure that all potentially affected tissue is removed, reducing the risk of residual disease.
  • Step 4: Hemostasis During the excision, the surgeon controls any bleeding that may occur using electrocautery or ligation techniques. This step is essential to maintain a clear surgical field and minimize complications.
  • Step 5: Drain Placement (if necessary) In some cases, a drain may be inserted to prevent fluid accumulation at the surgical site. This helps to reduce the risk of seroma formation and promotes better healing.
  • Step 6: Closure of the Wound After the lesion has been excised and hemostasis achieved, the surgical wound is closed using layered sutures. This technique helps to ensure proper healing and minimizes the risk of complications.

3. Post-Procedure

Post-procedure care following the excision of a breast lesion includes monitoring the surgical site for signs of infection, managing pain, and ensuring proper wound healing. Patients may be advised to avoid strenuous activities for a specified period to allow for recovery. Follow-up appointments are typically scheduled to assess the healing process and to discuss the pathology results of the excised tissue. If a drain was placed, instructions will be provided for its care and eventual removal. Patients should be informed about signs of complications, such as increased redness, swelling, or discharge from the incision site, and advised to contact their healthcare provider if these occur.

Short Descr EXCISION BREAST LESION
Medium Descr EXC BREAST LES PREOP PLMT RAD MARKER OPEN 1 LES
Long Descr Excision of breast lesion identified by preoperative placement of radiological marker, open; single lesion
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 1
CCS Clinical Classification 166 - Lumpectomy, quadrantectomy of breast

This is a primary code that can be used with these additional add-on codes.

19126 Addon Code MPFS Status: Active Code APC N ASC N1 CPT Assistant Article Illustration for Code Excision of breast lesion identified by preoperative placement of radiological marker, open; each additional lesion separately identified by a preoperative radiological marker (List separately in addition to code for primary procedure)
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
GC This service has been performed in part by a resident under the direction of a teaching physician
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
SG Ambulatory surgical center (asc) facility service
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
54 Surgical care only: when 1 physician or other qualified health care professional performs a surgical procedure and another provides preoperative and/or postoperative management, surgical services may be identified by adding modifier 54 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2011-01-01 Changed Short description changed.
2001-01-01 Changed Code description changed.
1994-01-01 Added First appearance in code book in 1994.
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