© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 19294 refers to the preparation of the tumor cavity with the placement of a radiation therapy applicator specifically for intraoperative radiation therapy (IORT) that is performed concurrently with a partial mastectomy. This procedure is a critical component of breast conservation therapy (BCT), which aims to remove malignant breast tumors while preserving as much healthy tissue as possible. During IORT, a targeted dose of radiation is delivered directly to the tumor bed immediately after the tumor is excised. This approach is designed to eliminate any microscopic residual tumor cells that may remain in the area, thereby reducing the risk of local recurrence of breast cancer. The procedure involves careful preparation of the tumor cavity, which includes separating the remaining breast tissue from the underlying pectoralis muscle and the skin. A protective disc is then placed beneath the breast tissue to shield vital organs such as the heart, lungs, and ribs from radiation exposure. Following this preparation, a radiation applicator tube is inserted into the tumor bed to facilitate the delivery of the radiation dose. Once the IORT is completed, both the applicator tube and the protective disc are removed. It is important to note that CPT® Code 19294 is reported separately in addition to the code(s) for the primary procedure(s) performed, such as the partial mastectomy, ensuring accurate billing and documentation of the services rendered.
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