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Official Description

Biopsy, muscle; deep

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 20205 refers to a deep muscle biopsy, which is a specific type of incisional biopsy performed on muscle tissue that is located deeper beneath the surface. This procedure is essential for obtaining a tissue sample from the muscle to facilitate the diagnosis of various muscle-related diseases. Conditions such as muscular dystrophy, myasthenia gravis, polymyositis, dermatomyositis, amyotrophic lateral sclerosis (ALS), Friedreich's ataxia, and infections caused by parasites like trichinosis or toxoplasmosis can be evaluated through this biopsy. The process begins with the careful cleansing of the planned biopsy site to minimize the risk of infection. Following this, a surgical incision is made in the muscle to access the deeper tissue, allowing for the collection of a sample. This sample is then sent for pathology examination, which is reported separately. It is important to note that CPT® Code 20205 is specifically designated for cases where a deeper incision and tissue dissection are necessary, distinguishing it from the related code 20200, which is used for superficial muscle biopsies.

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