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Official Description

Biopsy, vertebral body, open; lumbar or cervical

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 20251 refers to an open biopsy of the vertebral body specifically targeting the lumbar or cervical regions of the spine. This procedure is performed under general anesthesia, ensuring that the patient is completely unconscious and free from pain during the operation. The patient is positioned in a prone position, which means they lie flat on their stomach, allowing the surgeon access to the back. An incision is made above the specific vertebra that requires biopsy, enabling the surgeon to reach the underlying tissues. The surrounding muscles are carefully dissected to expose the vertebra for testing and diagnosis. During the procedure, a sample of tissue is excised from the vertebral body, which is crucial for pathological examination to determine any underlying conditions or diseases. After the tissue sample is obtained, the muscles are repositioned to their original state, and the incision is meticulously closed in layers to promote proper healing. It is important to note that for biopsies of the thoracic vertebrae, the appropriate code to use is 20250, while 20251 is specifically designated for lumbar or cervical vertebral biopsies.

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