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Official Description

Excision, tumor, soft tissue of neck or anterior thorax, subcutaneous; 3 cm or greater

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 21552 involves the excision of a tumor located in the soft tissue of the neck or anterior thorax, specifically when the tumor measures 3 cm or greater. Soft tissues encompass a variety of structures, including subcutaneous fat, connective tissue, fascia, muscles, tendons, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. Tumors that arise in these soft tissues can be either benign or malignant. Typically, benign tumors are treated through excision, while small malignant or indeterminate tumors may also be excised if they have well-defined margins. The approach to excising the tumor depends on its specific location within the soft tissue. This may involve incising the skin directly over the tumor, creating and elevating a skin flap, or making a series of incisions along natural skin creases to facilitate exposure of the tumor. Once the overlying tissue is dissected, the soft tissue mass is exposed, allowing for the excision of the tumor along with a margin of healthy tissue to ensure complete removal. In some cases, a frozen section may be performed to verify that all margins are free of tumor cells, which is a separate reportable procedure. After the tumor is excised, drains may be placed as necessary, and the surgical wound is typically closed in layers to promote proper healing. For tumors located in the subcutaneous fat or connective tissue that are less than 3 cm, CPT® Code 21555 is used, while CPT® Code 21552 is specifically designated for tumors measuring 3 cm or greater. Additionally, for tumors situated below the fascia, CPT® Code 21556 applies for masses less than 5 cm, and CPT® Code 21554 is used for those that are 5 cm or greater. It is important to note that subfascial soft tissue tumors include those found within muscle tissue.

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