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Official Description

Radical resection of tumor (eg, sarcoma), soft tissue of back or flank; less than 5 cm

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Radical resection of a tumor, specifically a soft tissue tumor located in the back or flank, is a surgical procedure denoted by CPT® Code 21935. This procedure is indicated for tumors that are less than 5 cm in size and may involve various types of soft tissues, including muscles, tendons, fat, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. Soft tissue tumors can be classified as benign or malignant, with radical resection primarily performed for malignant neoplasms, such as sarcomas. However, there are instances where benign tumors or those of indeterminate nature may also necessitate a radical resection. The surgical approach typically begins with making a skin incision directly over the tumor or creating and elevating a skin flap. Following this, the overlying subcutaneous and soft tissues are carefully dissected to expose the tumor mass. The procedure aims to remove the tumor en bloc, which means the tumor is excised along with a wide margin of surrounding healthy tissue to ensure complete removal. This radical approach may involve the excision of adjacent muscles, nerves, and blood vessels, depending on the tumor's location and extent. To confirm that all cancerous cells have been removed, a separately reportable frozen section may be performed during the procedure. If any margins are found to contain malignancy, additional tissue will be excised until all margins are confirmed to be free of tumor cells. Post-surgery, drains may be placed as necessary, and the surgical wound can be closed in layers, or additional reconstructive procedures may be performed if required. For tumors measuring 5 cm or greater, CPT® Code 21936 should be utilized instead.

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