© Copyright 2026 American Medical Association. All rights reserved.
Radical resection of a tumor in the soft tissue of the abdominal wall, as described by CPT® Code 22904, involves the surgical removal of a tumor that is less than 5 cm in size. Soft tissues encompass various structures, including muscles, tendons, fat, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. Tumors found in these soft tissues can be either benign or malignant, with radical resection primarily indicated for malignant neoplasms, such as sarcomas. However, there are instances where benign tumors or those of indeterminate nature may also necessitate a radical approach to ensure complete removal. The procedure typically begins with a skin incision made directly over the tumor or the creation of a skin flap that is then elevated. This allows for the dissection of the overlying subcutaneous and soft tissues to expose the tumor adequately. The surgical goal is to excise the tumor en bloc, which means removing it along with a wide margin of surrounding healthy tissue to ensure that no cancerous cells remain. This comprehensive approach may involve the excision of adjacent muscles, nerves, and blood vessels if they are involved with the tumor. To confirm that all margins are free of tumor cells, a separately reportable frozen section may be performed during the procedure. If any margins are found to contain malignancy, additional tissue will be excised until clear margins are achieved. Post-surgery, drains may be placed as necessary, and the surgical wound can be closed in layers, or additional reconstructive procedures may be performed if required. For tumors measuring 5 cm or greater, CPT® Code 22905 should be utilized instead of 22904.
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