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Official Description

Radical resection of tumor (eg, sarcoma), soft tissue of leg or ankle area; 5 cm or greater

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 27616 refers to the radical resection of a tumor located in the soft tissue of the leg or ankle area, specifically when the tumor measures 5 cm or greater. Soft tissues encompass a variety of structures, including muscles, tendons, fat, blood vessels, lymph vessels, nerves, and the tissues that surround joints. Tumors that arise in these soft tissues can be classified as either benign or malignant. However, radical resection is predominantly indicated for malignant neoplasms, such as sarcomas, although there are instances where benign tumors or those of indeterminate nature may also necessitate this extensive surgical intervention. During the procedure, a skin incision is made directly over the tumor site in the lower leg or ankle region, or alternatively, a skin flap may be created and elevated to provide access. The surgeon meticulously dissects the overlying tissue to expose the tumor. The goal of radical resection is to remove the tumor en bloc, which means the tumor is excised along with a wide margin of surrounding healthy tissue to ensure complete removal of any cancerous cells. This procedure may involve the excision of all affected soft tissue, which can include critical structures such as muscles, nerves, and blood vessels. To confirm that the surgical margins are free of tumor cells, a separately reportable frozen section may be performed during the procedure. If the margins are found to contain malignancy, additional tissue will be excised until clear margins are achieved. Post-surgery, drains may be placed as necessary to prevent fluid accumulation. The surgical wound is typically closed in layers, and in some cases, separately reportable reconstructive procedures may be performed to restore the area. For smaller tumors measuring less than 5 cm, the appropriate code to use is 27615, while CPT® Code 27616 is specifically designated for tumors that are 5 cm or greater.

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