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Percutaneous cryoablation therapy is a specialized medical procedure aimed at the reduction or eradication of one or more pulmonary tumors. This technique is particularly relevant when tumors extend to involve the pleura or chest wall. The procedure is performed unilaterally, meaning it targets one lung. Cryoablation is classified as a minimally invasive approach, making it a suitable option for patients who may not be candidates for traditional surgical resection due to various health concerns. It can also serve as a palliative treatment for patients with advanced tumors that are not amenable to removal because of their size or location. During the procedure, local anesthesia is administered to numb the skin and connective tissue down to the pleura, ensuring patient comfort. In some cases, moderate sedation may be utilized to further enhance comfort levels. The use of imaging guidance, such as computed tomography (CT), is integral to the procedure, allowing for precise placement of the cryoprobe into the tumor or targeted tissue area. The cryoprobe delivers high-pressure argon or helium gases to freeze the tissue, typically in a series of cycles that include periods of freezing and thawing. This process results in the formation of an ice ball, approximately 2-3 cm in diameter, within the affected tissue, which is subsequently left in place to be reabsorbed by the body over time.
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