© Copyright 2026 American Medical Association. All rights reserved.
Extracorporeal membrane oxygenation (ECMO) and extracorporeal life support (ECLS) are terms that refer to advanced medical procedures designed to provide long-term support for patients experiencing severe heart and lung failure. These procedures typically last from three to ten days and involve the circulation of blood outside the body through an artificial lung, which oxygenates the blood before returning it to the patient's bloodstream. In the case of veno-arterial (V-A) ECMO/ECLS, blood is drawn from a large central vein, oxygenated, and then returned to a major artery, effectively bypassing the heart and lungs. This method is particularly beneficial for patients suffering from critical cardiac failure, which may be accompanied by respiratory failure or may occur following surgical interventions on the heart. The management of V-A ECMO/ECLS requires continuous medical oversight, usually provided by an intensive care unit (ICU) intensivist, and involves a dedicated team of perfusion specialists who monitor the patient around the clock. The physician's role in the daily management of V-A ECMO/ECLS encompasses a variety of critical tasks, including the administration of sedation, anticoagulation therapy, temperature regulation, ensuring hemodynamic stability, and conducting analyses of electrolytes and blood gases, as well as providing respiratory or ventilator support as needed.
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