© Copyright 2026 American Medical Association. All rights reserved.
Extracorporeal membrane oxygenation (ECMO) and extracorporeal life support (ECLS) are terms that refer to advanced medical procedures designed to provide long-term support for patients with severe heart and lung dysfunction. These procedures involve the use of a machine that takes over the function of the heart and lungs by circulating blood outside the body through an artificial lung, where it is oxygenated before being returned to the bloodstream. This life-sustaining support is critical for patients who are unable to maintain adequate oxygenation and perfusion due to various medical conditions. The procedure described by CPT® Code 33966 specifically pertains to the removal of peripheral arterial and/or venous cannula(e) in patients aged 6 years and older. The removal process is performed with careful attention to technique to minimize complications, such as air embolism, and involves specific positioning of the patient and controlled withdrawal of the cannula(e). This procedure is essential in the management of patients who have been on ECMO/ECLS, as it marks a significant step in their recovery and transition away from mechanical support.
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