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Code deleted, see 37225, 37227.

Official Description

Transluminal peripheral atherectomy, percutaneous; femoral-popliteal

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 35493 refers to a specific medical procedure known as percutaneous transluminal atherectomy, which is performed on the femoral-popliteal artery. This procedure is utilized to remove plaque buildup from the arterial walls, thereby improving blood flow in patients with peripheral artery disease. The term "transluminal" indicates that the procedure is performed through the lumen of the artery, and "atherectomy" refers to the surgical removal of atherosclerotic plaque. During the procedure, a physician accesses the femoral artery, typically located in the groin area, and uses a needle to puncture the artery. A sheath is then placed to facilitate the introduction of instruments into the artery. A guidewire is advanced into the occluded artery, allowing for the insertion of an atherectomy catheter. This specialized catheter features a cutting piston that effectively shaves away plaque from the arterial wall. The removed plaque is collected within the device and expelled upon completion of the procedure. Following the atherectomy, an angiography catheter is used to perform a completion angiography, ensuring that the artery is open and blood flow is restored. The procedure concludes with the application of pressure to the puncture site to prevent bleeding, followed by the placement of a pressure dressing.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 35493 is indicated for patients experiencing significant arterial occlusion in the femoral-popliteal region, which may lead to symptoms such as claudication, rest pain, or critical limb ischemia. The following conditions may warrant the performance of this procedure:

  • Peripheral Artery Disease (PAD) - A condition characterized by narrowed arteries reducing blood flow to the limbs, often leading to pain and mobility issues.
  • Severe Atherosclerosis - The buildup of plaque in the arteries that can cause significant blockage and impede blood flow.
  • Intermittent Claudication - Pain or cramping in the legs or buttocks during physical activities, which is relieved by rest.
  • Rest Pain - Pain in the feet or toes while at rest, indicating severe arterial insufficiency.
  • Critical Limb Ischemia - A severe obstruction of blood flow to the extremities, which can lead to tissue loss and potential amputation if not treated.

2. Procedure

The procedure for CPT® Code 35493 involves several critical steps to ensure effective removal of plaque from the femoral-popliteal artery. The following outlines the procedural steps:

  • Step 1: Preparation and Access The physician begins by preparing the skin over the access artery, typically one of the femoral arteries, to minimize the risk of infection. A local anesthetic may be administered to ensure patient comfort. Once the area is prepped, the physician punctures the artery with a needle and places a sheath to facilitate access.
  • Step 2: Guidewire Insertion After establishing access, a guidewire is inserted through the sheath and advanced into the occluded artery. This guidewire serves as a pathway for the subsequent devices used in the procedure.
  • Step 3: Atherectomy Catheter Advancement The atherectomy catheter is then advanced over the guidewire into the occluded segment of the artery. Once positioned correctly, the guidewire is withdrawn, leaving the atherectomy catheter in place for the next step.
  • Step 4: Performing Atherectomy The atherectomy device is activated, utilizing a specialized balloon catheter that features a cutting piston. This piston is advanced through a window on the catheter, effectively shaving plaque from the arterial wall. The shaved plaque is collected in the nose of the atherectomy device.
  • Step 5: Multiple Passes The physician may perform several passes with the atherectomy device to ensure thorough removal of plaque and achieve optimal results in restoring blood flow.
  • Step 6: Completion Angiography Once the atherectomy is completed, the atherectomy device is exchanged for an angiography catheter. Contrast material is injected to visualize the artery, and a completion angiography is performed to confirm that the artery is patent and blood flow is restored.
  • Step 7: Closure and Dressing After the completion angiography, the angiography catheter is withdrawn. The physician applies pressure to the arterial puncture site to control any bleeding and subsequently places a pressure dressing to secure the site and promote healing.

3. Post-Procedure

Post-procedure care for patients undergoing CPT® Code 35493 involves monitoring the puncture site for any signs of bleeding or complications. Patients are typically advised to rest and avoid strenuous activities for a specified period to allow for proper healing. Follow-up appointments may be scheduled to assess the success of the procedure and monitor the patient's recovery. Additionally, patients may receive instructions regarding medication management, lifestyle modifications, and any necessary rehabilitation to improve overall vascular health.

Short Descr ATHERECTOMY, PERCUTANEOUS
Medium Descr TRLUML PRPH ATHRC PRQ FEMPOP
Long Descr Transluminal peripheral atherectomy, percutaneous; femoral-popliteal
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Significant Procedure, Multiple Reduction Applies
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 60 - Embolectomy and endarterectomy of lower limbs
Date
Action
Notes
2011-01-01 Deleted Code deleted, see 37225, 37227.
1993-01-01 Added Code added.
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