© Copyright 2026 American Medical Association. All rights reserved.
The procedure described by CPT® Code 36593 involves the use of a thrombolytic agent to declot an implanted vascular access device (IVAD) or a central venous catheter (CVC). Thrombolytic agents are medications that help dissolve blood clots, and examples include streptokinase, tissue-type plasminogen activator (t-PA), urokinase, and heparin. The process begins with the preparation of the thrombolytic agent according to the manufacturer's instructions, ensuring that the medication is ready for use. Prior to the instillation of the agent, the skin over the IVAD or the catheter hub is thoroughly cleansed to minimize the risk of infection. The thrombolytic agent is then instilled into the IVAD or into each lumen of the CVC, allowing it to target the thrombus obstructing the device. The agent is typically left in place for a specific dwell time, which can range from 30 to 60 minutes, as recommended by the drug manufacturer. After the dwell time has elapsed, the patency of the IVAD or catheter is assessed by attempting to draw blood or infuse fluids. If the obstruction persists, a second instillation of the thrombolytic agent may be performed to further address the clot. This procedure is critical for maintaining the functionality of vascular access devices, which are essential for patients requiring long-term intravenous therapy.
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