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Official Description

Vascular endoscopy, surgical, with ligation of perforator veins, subfascial (SEPS)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 37500 refers to a surgical technique known as vascular endoscopy, specifically involving the ligation of perforator veins in the subfascial space, commonly referred to as Subfascial Endoscopic Perforator Surgery (SEPS). Perforator veins are critical structures that connect the deep venous system, which includes the femoral and popliteal veins, to the superficial venous system, represented by the saphenous veins. In patients suffering from severe chronic venous insufficiency, these perforator veins can become incompetent, leading to complications such as venous ulcerations. The SEPS procedure aims to address these issues by interrupting the abnormal blood flow between the deep and superficial venous systems. This is achieved through a minimally invasive endoscopic approach, which utilizes ultrasound guidance to accurately locate the perforator veins. The procedure involves creating small incisions in the skin of the calf, allowing access to the subfascial space where the perforator veins are situated. By employing techniques such as insufflation with carbon dioxide and the use of specialized surgical instruments, the incompetent veins can be effectively clipped or divided, thereby improving venous function and promoting healing in affected patients.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The SEPS procedure is indicated for patients who exhibit the following conditions:

  • Chronic Venous Insufficiency - A condition characterized by the improper functioning of the venous valves, leading to inadequate blood flow from the legs back to the heart.
  • Venous Ulcerations - Open sores or wounds on the skin of the legs that occur due to poor circulation and are often associated with chronic venous insufficiency.
  • Incompetent Perforator Veins - Perforator veins that fail to function properly, allowing blood to flow backward and contributing to venous hypertension and related complications.

2. Procedure

The SEPS procedure involves several critical steps to ensure effective treatment of incompetent perforator veins:

  • Step 1: Ultrasound Guidance - The procedure begins with the use of ultrasound imaging to accurately identify the location of the incompetent perforator veins. This step is crucial for ensuring precise intervention during the surgery.
  • Step 2: Exsanguination of the Leg - The leg is exsanguinated to minimize blood flow to the area, which helps in reducing bleeding during the procedure and enhances visibility for the surgeon.
  • Step 3: Incision Creation - Two small portal incisions are made in the skin of the calf at sites that are remote from any existing venous ulcerations. These incisions are designed to provide access to the subfascial space without disturbing the ulcerated areas.
  • Step 4: Introduction of Space-Maker Balloon - A space-maker balloon is inserted into the subfascial space through the incisions and inflated. This step is performed to create a larger working area, facilitating better access to the perforator veins.
  • Step 5: Insufflation with Carbon Dioxide - The subfascial space is insufflated with carbon dioxide, which further expands the area and improves visibility for the surgical team.
  • Step 6: Ligation of Perforator Veins - The incompetent perforator veins are then clipped or divided using endoscopic scissors. Alternatively, a harmonic scalpel may be employed to coagulate and divide the veins, ensuring effective treatment.
  • Step 7: Closure of Incisions - Upon completion of the ligation, the surgical instruments are carefully removed, carbon dioxide is released from the subfascial space, and the portal incisions are closed to promote healing.

3. Post-Procedure

After the SEPS procedure, patients are typically monitored for any immediate complications. Post-procedure care may include instructions for wound care at the incision sites, recommendations for activity levels, and guidance on managing any discomfort. Patients may be advised to wear compression garments to support venous return and reduce swelling. Follow-up appointments are essential to assess healing and the effectiveness of the procedure in alleviating symptoms associated with chronic venous insufficiency and venous ulcerations.

Short Descr ENDOSCOPY LIGATE PERF VEINS
Medium Descr VASC ENDOSCOPY SURG W/LIG PERFORATOR VEINS SPX
Long Descr Vascular endoscopy, surgical, with ligation of perforator veins, subfascial (SEPS)
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8I - Endoscopy - other
MUE 1
CCS Clinical Classification 61 - Other OR procedures on vessels other than head and neck
LT Left side (used to identify procedures performed on the left side of the body)
Date
Action
Notes
2003-01-01 Added First appearance in code book in 2003.
1986-12-31 Deleted Code deleted.
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