© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 38205 refers to the process of harvesting blood-derived hematopoietic progenitor cells specifically for transplantation purposes. This procedure involves the collection of whole blood from a donor, which is then subjected to a specialized processing technique using a machine. The primary goal of this process is to separate hematopoietic progenitor cells, which are essential for the formation of blood cells, from other components of the blood. Once the hematopoietic progenitor cells are isolated, the remaining blood components, which may include plasma and red blood cells, are treated appropriately and reinfused back into the donor's circulation. This ensures that the donor's blood volume and composition are restored while allowing for the collection of the necessary cells for transplantation. It is important to note that this code is specifically used for allogeneic collections, meaning the cells are harvested from a donor other than the patient. For collections of cells derived from the patient's own blood, the appropriate code to use is 38206. Each instance of blood-derived donor cell collection is billed under code 38205.
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