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Official Description

Bone marrow harvesting for transplantation; autologous

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Bone marrow harvesting for transplantation, specifically autologous harvesting, is a medical procedure that involves the extraction of bone marrow from a patient’s own body. Bone marrow is a vital substance found within the inner cavities of bones, primarily responsible for producing hematopoietic progenitor cells (HPCs), also known as hematopoietic stem cells (HSCs). These cells are crucial as they have the ability to develop into various types of mature blood cells, including red blood cells, which carry oxygen; platelets, which are essential for blood clotting; and white blood cells, which play a key role in the immune response. During the procedure, the patient is positioned lying prone on the operating table, and general anesthesia is administered to ensure comfort and pain relief. The area over the iliac crest, which is the top part of the hip bone, is thoroughly cleansed to maintain a sterile environment. A specialized needle is then inserted through the skin and into the bone to access the bone marrow. The extraction process begins with the collection of bone marrow from the first puncture site using a syringe attached to the needle. After this initial collection, the needle is withdrawn from the bone but remains in the skin, allowing for repositioning at a different angle or site within the same bone. This technique is repeated multiple times at various sites on the iliac crest to maximize the amount of bone marrow harvested. Once sufficient marrow has been collected from one side, the procedure may be performed on the opposite side of the iliac crest. The goal is to harvest approximately 2 quarts of bone marrow, which can then be used for transplantation purposes, particularly in treating conditions such as certain cancers or blood disorders. It is important to note that CPT® Code 38232 is specifically designated for autologous bone marrow harvesting, while a different code, 38230, is used when the bone marrow is harvested from a donor (allogeneic).

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