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Official Description

Biopsy; nasopharynx, visible lesion, simple

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 42804 involves a biopsy of the nasopharynx, specifically targeting a visible lesion. The nasopharynx is anatomically located at the upper part of the pharynx, which connects to the nasal passages. In this procedure, a simple biopsy is conducted, which entails the removal of one or more tissue samples from the identified lesion. Prior to the biopsy, a local anesthetic is administered to minimize discomfort for the patient during the procedure. The collected tissue samples are then sent for laboratory analysis, which is reported separately. This procedure is distinct from other biopsy codes, such as CPT® Code 42806, which involves a more extensive biopsy for cases where the primary lesion is unknown and typically requires a larger tissue sample and general anesthesia. The simplicity of the biopsy in CPT® Code 42804 is characterized by its focus on visible lesions and the use of local anesthesia, making it a less invasive option for diagnostic purposes.

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