© Copyright 2026 American Medical Association. All rights reserved.
Esophagoscopy, flexible, transoral, is a medical procedure that involves the use of a flexible endoscope to visualize the esophagus. This procedure is performed by introducing the endoscope through the mouth and advancing it into the distal esophagus. During the examination, various anatomical structures are assessed, including the velopharyngeal closure, the base of the tongue, and the hypopharynx. The motion of the vocal cords is observed, and the pharyngeal musculature is evaluated to ensure proper function. As the endoscope reaches the cricopharyngeus, the patient may be instructed to burp or swallow, which aids in the smooth passage of the scope through the esophagus to the gastroesophageal junction. Any abnormalities encountered during this process are meticulously noted for further evaluation. In conjunction with the esophagoscopy, transendoscopic ultrasound (EUS) is utilized to provide detailed imaging of the thoracic region. A radial scanning echoendoscope is introduced under direct visualization to assess the mediastinum and surrounding structures for enlarged lymph nodes and other lesions. This imaging helps determine the origin of any identified tumors, whether they are arising from the esophagus or other nearby structures, and whether there is any invasion into vital structures. Additionally, the lungs are evaluated for pleural effusion and other potential abnormalities. The ultrasound images captured during the procedure are printed for further analysis. Following the imaging, a linear scanning echoendoscope is used to perform fine needle aspiration or biopsy of any lymph nodes or lesions that are accessible through the esophagus. A needle biopsy catheter is advanced through the echoendoscope's biopsy channel, and Doppler imaging is employed to ensure that no vascular structures obstruct the biopsy path. The needle is then carefully advanced through the esophageal wall into the targeted lesion or lymph node to obtain an aspiration biopsy, which is subsequently sent for cytologic evaluation. Multiple passes may be made at each biopsy site to ensure an adequate specimen is collected, with the biopsy device being cleaned and reassembled after each pass before proceeding to the next site.
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