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Official Description

Endoscopic retrograde cholangiopancreatography (ERCP); with biopsy, single or multiple

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Endoscopic retrograde cholangiopancreatography (ERCP) is a specialized diagnostic procedure that allows for the examination of the pancreatic and biliary ducts, which are critical pathways for the drainage of digestive fluids from the pancreas, liver, and gallbladder. This procedure is particularly valuable in diagnosing various conditions affecting the bile ducts, including obstructions, infections, and malignancies. During an ERCP, a flexible endoscope is inserted through the patient's mouth, traversing the esophagus and stomach, and advancing into the duodenum, where the pancreatic duct and common bile duct converge at a location known as the ampulla of Vater. At this juncture, a smaller catheter is introduced through the endoscope to cannulate the ampulla of Vater, allowing for the injection of contrast dye into the ducts. This contrast material is essential for visualizing the anatomy and any pathological changes within the common bile duct, biliary tract, gallbladder, and pancreas via X-ray imaging. The procedure not only aids in identifying issues such as gallstones, strictures, leaks, scarring, or tumors but also facilitates the collection of tissue samples through brushing or saline washing techniques. The use of CPT® code 43261 is appropriate when one or more biopsies are performed during the ERCP, enabling healthcare providers to obtain histological samples for further analysis and diagnosis.

© Copyright 2026 Coding Ahead. All rights reserved.

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