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Official Description

Endoscopic retrograde cholangiopancreatography (ERCP); with destruction of calculi, any method (eg, mechanical, electrohydraulic, lithotripsy)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Endoscopic retrograde cholangiopancreatography (ERCP) is a specialized medical procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions affecting the biliary and pancreatic ducts. This procedure is particularly significant for patients with obstructive jaundice, pancreatitis, or other biliary tract disorders. During ERCP, an endoscope—a flexible tube equipped with a camera and light—is inserted through the mouth, passing through the esophagus and stomach, and into the duodenum. The procedure specifically targets the ampulla of Vater, where the pancreatic duct and common bile duct converge. This location is critical for visualizing and accessing the ducts for further intervention. In the context of CPT® Code 43265, the procedure involves not only the visualization of these ducts but also the removal and destruction of gallstones (calculi) that may be obstructing the flow of bile or pancreatic juices. The destruction of these stones can be achieved through various methods, including mechanical means, electrohydraulic techniques, or lithotripsy, which utilizes shock waves to break the stones into smaller, passable fragments. The ability to perform both diagnostic and therapeutic actions during a single ERCP session makes it a valuable tool in managing biliary and pancreatic conditions effectively.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

ERCP is indicated for a variety of conditions affecting the biliary and pancreatic systems. The following are explicitly provided indications for performing this procedure:

  • Obstructive Jaundice - This condition occurs when there is a blockage in the bile duct, leading to a buildup of bile in the liver and subsequent jaundice.
  • Cholelithiasis - The presence of gallstones in the gallbladder or bile ducts, which can cause pain, inflammation, and obstruction.
  • Pancreatitis - Inflammation of the pancreas, which may be caused by gallstones obstructing the pancreatic duct.
  • Biliary Strictures - Narrowing of the bile ducts that can impede the flow of bile and lead to complications.
  • Cholangitis - Infection of the bile duct system, often associated with obstruction due to stones or strictures.

2. Procedure

The ERCP procedure involves several critical steps to ensure effective diagnosis and treatment. The following procedural steps are outlined:

  • Step 1: Endoscope Insertion - The procedure begins with the insertion of an endoscope through the patient's mouth, advancing it through the esophagus and stomach, and into the duodenum. This allows the physician to visualize the ampulla of Vater, where the pancreatic duct and common bile duct meet.
  • Step 2: Cannulation and Contrast Injection - A smaller catheter is introduced through the endoscope to cannulate the ampulla of Vater. Once cannulated, contrast dye is injected into the biliary and pancreatic ducts. This step is crucial for visualizing the ducts on X-ray images, which are taken immediately after the dye injection.
  • Step 3: Stone Removal - If calculi or debris are present, a balloon catheter is inserted and maneuvered past the obstructing stone. The balloon is then inflated, allowing for the stone to be extracted through slow withdrawal of the balloon catheter. Alternatively, a basket extraction technique may be employed, where a basket device is used to trap the stone before withdrawal.
  • Step 4: Calculi Destruction - For stones that cannot be removed intact, a catheter is advanced over a guidewire to the site of the gallstone. Mechanical destruction may be performed using a crushing basket device, which traps and crushes the stone. Alternatively, electrohydraulic or laser lithotripsy devices can be utilized to shatter the stone into smaller fragments, facilitating easier removal.

3. Post-Procedure

After the ERCP procedure, patients are typically monitored for any immediate complications, such as pancreatitis, bleeding, or infection. Recovery may involve observation in a healthcare setting until the patient is stable. Patients may experience mild discomfort or bloating due to the air introduced during the procedure. It is essential for healthcare providers to provide post-procedure instructions, including dietary recommendations and signs of potential complications that should prompt immediate medical attention. Follow-up appointments may be necessary to assess the effectiveness of the procedure and to plan any further treatment if required.

Short Descr ERCP LITHOTRIPSY CALCULI
Medium Descr ERCP DESTRUCTION/LITHOTRIPSY CALCULI ANY METHOD
Long Descr Endoscopic retrograde cholangiopancreatography (ERCP); with destruction of calculi, any method (eg, mechanical, electrohydraulic, lithotripsy)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 3 - Special payment adjustment rules for multiple endoscopic procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Endoscopic Base Code 43260  Endoscopic retrograde cholangiopancreatography (ERCP); diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8B - Endoscopy - upper gastrointestinal
MUE 1
CCS Clinical Classification 82 - Endoscopic retrograde cannulation of pancreas (ERCP)

This is a primary code that can be used with these additional add-on codes.

0397T Addon Code MPFS Status: Carrier Priced APC N ASC N1 Endoscopic retrograde cholangiopancreatography (ERCP), with optical endomicroscopy (List separately in addition to code for primary procedure)
43273 Addon Code MPFS Status: Active Code APC N ASC N1 CPT Assistant Article Illustration for Code Endoscopic cannulation of papilla with direct visualization of pancreatic/common bile duct(s) (List separately in addition to code(s) for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
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2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2014-01-01 Changed Description Changed
2002-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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