CPT® Code 48105

Resection or debridement of the pancreas and peripancreatic tissue is a surgical procedure performed to address acute necrotizing pancreatitis, a severe condition characterized by the destruction of pancreatic tissue due to inflammation. This inflammation is primarily caused by the autodigestion of the pancreas by its own digestive enzymes, leading to the formation of parenchymal abscesses and potential hemorrhaging. In acute necrotizing pancreatitis, the pancreas and surrounding tissues become necrotic, which can result in significant complications if not managed appropriately. The procedure involves the careful removal of necrotic tissue, which may include both the pancreas itself and the peripancreatic fat, as the latter is typically the first to undergo necrosis. Surgical intervention is generally considered only when there is evidence of bacterial or fungal infection within the necrotic tissue, as indicated by Gram stain or culture results from aspirated samples. The goal of the surgery is to remove infected and necrotic tissue to prevent further complications and promote recovery, while minimizing the risk to the patient. An abdominal incision is made to access the pancreas, and the surrounding tissues are meticulously dissected and retracted to allow for adequate visualization and access to the affected areas. After the necrotic tissue is excised, drains are placed to facilitate fluid management, and the surgical site is subsequently closed.