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Official Description

Removal of transplanted pancreatic allograft

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 48556 involves the surgical removal of a transplanted pancreatic allograft. This operation is typically necessitated by complications that may arise post-transplant, such as graft rejection, which occurs when the recipient's immune system attacks the transplanted organ, or due to infection, where the allograft becomes compromised by bacterial or viral pathogens. Additionally, malignancy, or the presence of cancerous cells within the transplanted pancreas, can also warrant its removal. The surgical process begins with an incision in the abdomen to access the transplanted pancreas. Once the allograft is visualized, the surgeon evaluates its condition to confirm that it is not functioning adequately. If the decision is made to proceed with the removal, the surgeon will clamp and transect the donor portal vein and donor iliac artery to prevent blood loss. The vascular anastomosis sites, where the allograft was connected to the recipient's blood vessels, are then repaired to restore normal blood flow. The pancreas is detached at the anastomosis sites, which may be located in the jejunum (part of the small intestine) or the urinary bladder, depending on the original surgical technique used for transplantation. After the pancreas is removed, the sites of the jejunum or urinary bladder are repaired, drains may be placed to prevent fluid accumulation, and the abdominal cavity is subsequently closed. This procedure is critical in managing complications associated with pancreatic transplants and ensuring the health and safety of the recipient.

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