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Official Description

Sclerotherapy of a fluid collection (eg, lymphocele, cyst, or seroma), percutaneous, including contrast injection(s), sclerosant injection(s), diagnostic study, imaging guidance (eg, ultrasound, fluoroscopy) and radiological supervision and interpretation when performed

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 49185 involves sclerotherapy, which is a minimally invasive technique used to treat fluid collections such as lymphoceles, cysts, or seromas. During this procedure, a chemical agent known as a sclerosant is injected into the fluid-filled cavity to induce inflammatory fibrosis of the lesion wall. This process helps to prevent the re-accumulation of fluid within the cavity. The procedure begins with the insertion of a small-bore needle through the skin into the lesion, followed by the placement of a pigtail catheter. This catheter allows for the aspiration of the fluid, which is then measured and sent for laboratory analysis, including tests such as Gram stain, culture, and cytology. To ensure the safety and effectiveness of the sclerotherapy, diluted contrast dye is injected through the catheter and monitored using imaging techniques like fluoroscopy. This step is crucial to rule out any potential communication between the cyst or fluid cavity and surrounding structures, such as the peritoneum, blood vessels, biliary system, or renal collecting system. If any communication is detected, the injection of the sclerosant is contraindicated. Once it is confirmed that there is no leakage, approximately 50% of the aspirated fluid volume is replaced with the sclerosant, with ethanol being the most commonly used agent. Other sclerosants may include bismuth, povidone-iodine, tetracycline, bleomycin, hypertonic saline, ethanolamine oleate, and acetic acid. The patient's position is adjusted to ensure that the sclerosant makes contact with the entire cyst wall. After allowing the sclerosant to act for a minimum of 20 minutes, it is then removed via aspiration. The catheter may be connected to bulb suction, and imaging studies such as ultrasound or computed tomography are performed to confirm the complete evacuation of the sclerosant. Depending on the treatment plan, the catheter may be removed immediately or left in place for potential future treatments. CPT® Code 49185 encompasses all necessary imaging guidance and the associated supervision and interpretation required during the sclerotherapy procedure.

© Copyright 2026 Coding Ahead. All rights reserved.

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