© Copyright 2026 American Medical Association. All rights reserved.
An open nephrectomy, as described by CPT® Code 50225, is a surgical procedure that involves the removal of a kidney along with a partial ureterectomy, which is the surgical removal of a portion of the ureter, the tube that carries urine from the kidney to the bladder. This procedure is performed through an open approach, which may include rib resection if necessary to gain adequate access to the kidney. The surgery is considered complicated when there has been previous surgical intervention on the same kidney, which may alter the normal anatomy and increase the difficulty of the procedure. The operation typically begins with a wide flank incision made below the lower border of the ribs or near the 11th or 12th rib, allowing the surgeon to access the kidney directly. In some cases, the 11th and/or 12th ribs may need to be removed to facilitate this access. The surgical team carefully exposes the kidney and ureter, isolates the renal artery and vein, and proceeds to ligate and divide these vessels to detach the kidney from its blood supply. The kidney is then dissected free from the surrounding tissues, and a section of the ureter is removed along with the kidney. This procedure is critical in treating various kidney conditions, particularly when previous surgeries have complicated the anatomy and necessitated a more extensive surgical approach.
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