© Copyright 2026 American Medical Association. All rights reserved.
An open radical nephrectomy is a surgical procedure that involves the removal of a kidney along with a portion of the ureter, and may include the excision of regional lymph nodes and the removal of any tumor thrombus present in the renal vein or vena cava. This procedure is typically indicated for patients with kidney cancer or other significant renal pathologies. The surgery is performed through a wide flank incision, which is strategically placed below the lower border of the ribs or near the 11th or 12th rib to provide optimal access to the kidney. In some cases, the 11th and/or 12th ribs may be resected to facilitate the surgical approach. The procedure may also utilize an anterior subcostal approach, depending on the specific circumstances of the case. During the operation, the surgeon carefully dissects the kidney and ureter, isolates the renal artery and vein, and assesses for any tumor thrombus. If thrombus is detected, it is managed appropriately to ensure complete removal. The surrounding structures, including the adrenal gland, may also be excised if necessary. The procedure concludes with meticulous control of bleeding, placement of drains if required, and closure of the incision with sutures to promote healing.
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