© Copyright 2026 American Medical Association. All rights reserved.
The procedure described by CPT® Code 50280 involves the surgical treatment of one or more cysts located in the kidney. This is achieved through either excision or unroofing of the cysts. In this surgical intervention, a wide incision is made in the flank area, which allows the surgeon to access and expose the affected kidney. Once the kidney is visible, the cyst is opened to allow for the drainage of its fluid content. Following this, the cyst wall, which may be redundant, is completely excised using both blunt and sharp dissection techniques. To prevent the recurrence of the cyst, the base of the cyst is fulgurated, a process that involves the application of heat to destroy tissue. After the cyst has been addressed, the defect left behind is filled with perirenal fat to aid in healing. Alternatively, if an unroofing procedure is performed, the surgeon creates a window in the cyst wall or partially removes it, followed by marsupialization, which results in an open pocket formed by the remaining cyst wall. In some cases, drains may be inserted into the created window to facilitate ongoing drainage, and the remaining cyst wall is then closed around these drains. Throughout the procedure, careful attention is given to controlling any bleeding, and the surgical incisions are subsequently closed to complete the operation.
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