CPT® Code 50391

Instillation(s) of therapeutic agent into renal pelvis and/or ureter through established nephrostomy, pyelostomy or ureterostomy tube (eg, anticarcinogenic or antifungal agent)

The procedure described by CPT® Code 50391 involves the instillation of a therapeutic agent directly into the renal pelvis and/or ureter. This is accomplished through an established nephrostomy, pyelostomy, or ureterostomy tube. The therapeutic agents used in this procedure can include anticarcinogenic agents, which are designed to treat cancer, or antifungal agents that target infections such as those caused by Candida albicans. The procedure is typically indicated for patients with malignancies affecting the epithelial lining of the urinary tract or for those suffering from fungal infections in the renal pelvis. Prior to the instillation, fluoroscopic guidance may be utilized to confirm the correct positioning of the existing nephrostomy, pyelostomy, or ureterostomy tube. Once the position is verified, the therapeutic agent is prepared in a syringe and connected to the ostomy tube for instillation into the kidney or ureter. After the agent has been administered, it is retained for a specified duration before being drained and disposed of appropriately. Finally, the ostomy tube is reconnected to the drainage system to ensure continued urinary flow.