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Official Description

Urethroplasty, 2-stage reconstruction or repair of prostatic or membranous urethra; second stage

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 53425 refers to a two-stage urethroplasty specifically for the reconstruction or repair of the prostatic or membranous urethra, focusing on the second stage of this surgical intervention. This type of urethroplasty is typically indicated in cases where there has been injury or trauma to the urethra, which may arise from various conditions such as pelvic fractures, prostate surgeries, or radiation therapy. The prostatic and membranous urethra are critical components of the urinary tract, extending from the bladder neck through the prostate gland and terminating at the bulbar segment. The first stage of this procedure, coded as CPT® 53420, involves a perineal approach where a midline incision is made to access the urethra, allowing for the identification and treatment of strictures or transections. During this initial stage, a buccal mucosal graft is often utilized to repair the urethral defect. The second stage, represented by CPT® 53425, is performed after the graft has adequately vascularized, ensuring that sufficient epithelial tissue is present for successful reconstruction. This stage involves the mobilization of the graft and the creation of a neourethra, which is a tubular structure formed around a Foley catheter, ultimately restoring the continuity of the urethra and facilitating normal urinary function.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure coded as CPT® 53425 is indicated for the reconstruction or repair of the prostatic or membranous urethra following specific conditions that may compromise the integrity of the urethra. These indications include:

  • Pelvic Fracture: Trauma resulting from a fracture in the pelvic region can lead to injury of the urethra, necessitating surgical intervention.
  • Prostate Surgery: Surgical procedures involving the prostate may inadvertently damage the urethra, requiring repair through urethroplasty.
  • Radiation Therapy: Patients who have undergone radiation treatment for prostate cancer may experience urethral damage, leading to strictures or other complications that warrant reconstruction.

2. Procedure

The second stage of the two-stage urethroplasty procedure, as described by CPT® 53425, involves several critical steps to ensure successful reconstruction of the urethra. The procedure begins with the patient positioned appropriately, and a previously placed suprapubic catheter is maintained to divert urine. The surgeon makes a circumferential incision around the graft at the perineal edge, carefully mobilizing it laterally to prepare for the next steps. Following this, a Foley catheter is inserted transurethrally into the bladder to facilitate the formation of a neourethra. The mobilized graft is then rolled into a tubular structure around the Foley catheter, effectively creating a new urethral channel. This graft is secured in place with sutures at both the proximal and distal edges of the stricture opening or the urethral stumps, ensuring stability and proper alignment. Additionally, drains may be placed to manage any postoperative fluid accumulation. The corpus spongiosum is then closed over the newly formed urethra, followed by the closure of the bulbospongiosum muscle. Finally, the skin is closed, completing the surgical procedure while ensuring that both the suprapubic catheter and the transurethral catheter remain in place for continued urinary diversion and monitoring.

3. Post-Procedure

After the completion of the second stage of the urethroplasty, patients are typically monitored for any complications related to the surgical site and the newly formed urethra. The presence of both the suprapubic catheter and the transurethral catheter allows for effective management of urine output and minimizes the risk of urinary retention or obstruction. Patients may be advised on specific post-operative care instructions, including signs of infection, proper catheter care, and activity restrictions to promote healing. Follow-up appointments are essential to assess the success of the graft and the overall function of the urethra, ensuring that any issues can be addressed promptly. The expected recovery period may vary based on individual patient factors and the complexity of the procedure, but careful adherence to post-operative guidelines is crucial for optimal outcomes.

Short Descr RECONSTRUCT URETHRA STAGE 2
Medium Descr URTP 2-STG RCNSTJ/RPR PROSTAT/URETHRA 2ND STAGE
Long Descr Urethroplasty, 2-stage reconstruction or repair of prostatic or membranous urethra; second stage
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 1
CCS Clinical Classification 109 - Procedures on the urethra
GC This service has been performed in part by a resident under the direction of a teaching physician
Date
Action
Notes
2011-01-01 Changed Short description changed.
2009-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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