© Copyright 2026 American Medical Association. All rights reserved.
Transurethral destruction of prostate tissue by radiofrequency thermotherapy, commonly referred to as transurethral needle ablation (TUNA), is a minimally invasive procedure designed to alleviate symptoms associated with benign prostatic hypertrophy (BPH). BPH is a condition characterized by the enlargement of the prostate gland, which can lead to urinary difficulties such as increased frequency, urgency, and obstructed urine flow. During this procedure, the patient remains awake and is positioned in a dorsal lithotomy stance, which facilitates access to the urethra. To ensure patient comfort, an antiseptic solution is applied to the penis, and a local anesthetic, typically 10-20 mL of 1-2% lidocaine gel, is instilled into the urethra. This local anesthesia helps to minimize discomfort during the procedure. A rectal probe may be utilized to monitor the temperature of the prostate tissue throughout the treatment, ensuring that the applied heat is effective yet safe. A specialized catheter is then inserted into the prostatic urethra, through which an interstitial radiofrequency needle is deployed into the prostatic tissue. The needle contains bipolar electrodes that are activated by a radiofrequency machine, generating low-wave radiofrequency energy. This energy produces heat ranging from 60 to 100 degrees Celsius, effectively destroying excess prostatic tissue within a matter of minutes. To protect the surrounding urethral tissue from thermal damage, water is circulated through the catheter to cool the urethra during the procedure. The needle is systematically withdrawn and repositioned to treat all lobes of the prostate, ensuring comprehensive treatment. Upon completion of the procedure, the treatment catheter is removed, and a Foley catheter may be inserted transurethrally if necessary for post-procedure care.
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