© Copyright 2026 American Medical Association. All rights reserved.
Cryosurgical ablation of the prostate is a minimally invasive procedure primarily utilized for the treatment of prostate cancer. This technique may be employed as an initial treatment option or as a subsequent intervention following the failure of other therapies, such as radiation therapy. The procedure involves the use of cryoprobes, which are specialized instruments designed to freeze and destroy cancerous tissue within the prostate. To facilitate accurate placement of these probes, an ultrasound probe is inserted into the rectum, allowing for real-time imaging and monitoring during the procedure. This imaging is crucial for ensuring that the cryoprobes are positioned correctly within the prostate tissue. Once the probes are in place, they are cooled to create an ice ball, which effectively targets and ablates the cancerous cells. The growth of the ice ball is continuously monitored via ultrasound to ensure it reaches the desired size for effective treatment. Following the freezing phase, the cryoprobes may undergo a thawing process, and in some cases, a second freeze/thaw cycle is performed to enhance the treatment's effectiveness. Additionally, if necessary, a third freeze/thaw cycle may be applied to specific areas, such as the urethral diaphragm, to ensure comprehensive treatment. After the procedure, the cryoprobes are thawed and removed, and the entry sites in the perineum are typically closed with sutures to promote healing.
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