© Copyright 2026 American Medical Association. All rights reserved.
Transperineal placement of needles or catheters into the prostate is a specialized medical procedure utilized for the application of interstitial radioelements, commonly referred to as brachytherapy. This technique involves the insertion of radioactive isotopes directly into the prostate gland, allowing for a localized and controlled delivery of radiation therapy. The primary objective of this procedure is to treat prostate cancer by delivering radiation directly to the tumor while minimizing exposure to the surrounding healthy tissues. The procedure is performed through the perineum, which is the area between the scrotum and the anus, using precise applicators such as needles or small catheter tubes. Prior to the procedure, the prostate is mapped out using imaging techniques to identify the optimal locations for seed placement. The radioactive seeds, typically containing isotopes like iodine-125 or palladium-103, are implanted into the prostate tissue, where they emit radiation over a period of several months. This method ensures that the cancerous cells receive a targeted dose of radiation, enhancing treatment efficacy while reducing potential side effects associated with external beam radiation therapy. Once the radioactive seeds have delivered their therapeutic dose, they become inert and do not require removal, posing no further risk to the patient.
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