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Official Description

Artificial insemination; intra-cervical

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Artificial insemination is a medical procedure used to assist individuals or couples facing infertility challenges. The CPT® Code 58321 specifically refers to intra-cervical artificial insemination, which involves the introduction of sperm directly into the cervical canal. This procedure is typically indicated for male infertility issues, such as the absence of sperm, low sperm count, or conditions like retrograde ejaculation. Additionally, female infertility may necessitate this procedure due to cervical injuries or deformities that obstruct the passage of sperm through the cervix, the absence of a male partner, or other underlying factors contributing to infertility. During the procedure, a thin, flexible catheter is carefully inserted into the cervical os, which is the opening of the cervix, and is connected to a syringe that contains washed and concentrated sperm. The sperm is then injected into the cervical os, allowing for the possibility of fertilization to occur naturally within the female reproductive system.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

Artificial insemination, specifically intra-cervical, is indicated for various infertility issues affecting both males and females. The following conditions may warrant the use of this procedure:

  • Male Infertility This includes cases where there is an absence of sperm, a low sperm count, or retrograde ejaculation, which is a condition where sperm is not expelled normally during ejaculation.
  • Female Infertility This may be due to cervical injuries or deformities that prevent sperm from passing through the cervix, the absence of a male partner, or other reasons that contribute to difficulties in achieving pregnancy.

2. Procedure

The procedure for intra-cervical artificial insemination involves several key steps that ensure the effective introduction of sperm into the cervical canal. The following outlines the procedural steps:

  • Step 1: Preparation The patient is prepared for the procedure, which may include a thorough evaluation of their medical history and fertility status. The sperm sample is collected, washed, and concentrated to enhance the chances of successful fertilization.
  • Step 2: Catheter Insertion A thin, flexible catheter is carefully inserted into the cervical os, which is the opening of the cervix. This step requires precision to ensure that the catheter is positioned correctly for optimal sperm delivery.
  • Step 3: Sperm Injection Once the catheter is in place, it is connected to a syringe containing the prepared sperm. The sperm is then injected into the cervical os, allowing it to travel through the cervix and into the uterus, where fertilization may occur.

3. Post-Procedure

After the intra-cervical artificial insemination procedure, patients may be advised to rest for a short period. It is common for healthcare providers to recommend monitoring for any signs of discomfort or complications. Patients may also be instructed on when to take a pregnancy test to determine if the procedure was successful. Follow-up appointments may be scheduled to assess the outcome and discuss any further steps if necessary.

Short Descr ARTIFICIAL INSEMINATION
Medium Descr ARTIFICIAL INSEMINATION INTRA-CERVICAL
Long Descr Artificial insemination; intra-cervical
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 1
CCS Clinical Classification 131 - Other non-OR therapeutic procedures, female organs
Date
Action
Notes
1994-01-01 Added First appearance in code book in 1994.
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