© Copyright 2026 American Medical Association. All rights reserved.
Chorionic villus sampling (CVS) is a prenatal diagnostic procedure that involves obtaining a tissue sample from the chorionic villi, which are tiny, finger-like projections that form part of the placenta. This procedure is typically performed between the 9th and 12th weeks of pregnancy and is used to detect genetic abnormalities and other conditions in the fetus. The chorionic villi contain the same genetic material as the fetus, making them a valuable source for genetic testing. CVS can be performed using different methods, primarily transvaginal or transabdominal approaches. In both methods, the physician first cleanses the vagina and cervix with an antiseptic solution to minimize the risk of infection. Ultrasonic guidance is employed to ensure accurate placement of the catheter or needle, allowing for the safe aspiration of placental cells. The procedure is minimally invasive, but it requires careful technique and monitoring to ensure the safety of both the mother and the fetus.
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